30th May 2023 - 2nd June 2023 | Bizkaia Aretoa | Bilbao | Spain | Europe

Programme

The preliminary programme for the IPCC 2023, 25th International Pigment Cell Conference is below.
This programme is subject to modifications.

See the detailed programme.

Programme May 30-31 Programme June 1-2
Last version: 10/10/2022

Tuesday, May 30th

Hall
08:00-14:30 Attendees registration
Council meeting Etxepare room
08:30-10:00 Regional society council meeting PASPCR
Council meeting Elhuyar room
08:30-10:00 Regional society council meeting JSPCR
Council meeting Baroja room
08:30-10:00 Regional society council meeting ESPCR
Council meeting Arriaga room
08:30-10:00 Regional society council meeting ASPCR
Chillida and Axular rooms
10:00-10:30 Coffee break
Council meeting Arriaga room
10:30-11:30 Council meeting IFPCS
Institutional welcome - Opening session Mitxelena room
11:30-11:35 Welcome

Mª Dolores BOYANO LÓPEZ 1

1 Chair of the IPCC 2023, University of the Basque Country (UPV/EHU), Bilbao, Spain

11:35-11:40 Speech

Koldo CALLADO 1

1 Director of Scientific and Social Development, UPV/EHU, Bilbao, Spain

11:40-11:45 Speech

Gonzalo OLABARRIA 1

1 Councillor for the Mayor's Office and Culture, Bilbao City Council, Bilbao, Spain

11:45-11:55 Handover of the IPCC2020 torch to IPCC2023 by Prof. Tamio Suzuki
11:55-12:05 Speech

Yoko FUNASAKA 1

1 Nippon Medical School · Department of Dermatology, Tokyo, Japan

12:05-12:15 Kresala dantza taldea
12:20-12:30 Welcome and presentation of the opening lecture by Dr. Greg BARSH

Lluis MONTOLIU 1

1 National Center For Biotechnology (CNB-CSIC) and CIBER of Rare Diseases (CIBERER - ISCIII), Madrid, Spain

12:30-13:00 Genetics and genomics of mammalian color patterns

Greg BARSH 1

1 HudsonAlpha Institute and Stanford University, Standford, United States of America

Chillida and Axular rooms
13:00-14:30 Welcome reception
Plenary 1 - Opening session Mitxelena room
Chairpersons:
Yoko FUNASAKA, Nippon Medical School · Department of Dermatology, Japan
Lluis MONTOLIU, National Center For Biotechnology (CNB-CSIC) and CIBER of Rare Diseases (CIBERER - ISCIII), Spain
14:30-15:00 Light and pigment cell

Yoko FUNASAKA 1

1 Nippon Medical School · Department of Dermatology, Tokyo, Japan

15:00-15:20 2023 ESPCR HS Raper Medal
Tracking the melanogenic pathway to unravel the functional role of melanins: the bottom-up approach

Alessandra NAPOLITANO 1

1 University of Naples Federico II, Naples, Italy

15:20-15:40 2023 IFPCS Myron Gordon Award
Painting the neural crest: how studying pigment cells illuminates neural crest cell biology

Robert KELSH 1

1 University Of Bath, Bath, United Kingdom

15:40-15:45 2023 IFPCS Seiji Memorial Lecture

Will be delivered in Plenary 6

15:45-16:05 2023 JSPCR Takeuchi Medal
Genetic compensation for Kit loss of function mutation engaged possibly by the global gene expression change.

Takahiro KUNISADA 1

1 Department of Tissue and Organ Development, Gifu, Japan

16:05-16:25 2023 PASPCR Aaron Lerner Award
Mouse models of melanoma

David FISHER 1 , Suzie CHEN 2

1 Massachusetts General Hospital, Boston, Massachusetts, United States of America
2 Rutgers University, Piscataway, NJ, United States of America

16:25-16:45 2023 PCMR Thomas B. Fitzpatrik Medal
Role of autophagy in skin pigmentation

Sang Ho OH 1

1 Yonsei University College Of Medicine, Seoul, Republic of Korea

Chillida and Axular rooms
16:45-17:15 Coffee break
Plenary 2 - Pigmentation genetics Mitxelena room
Chairpersons:
Tamio SUZUKI, Department Of Dermatology, Faculty Of Medicine, Yamagata University, Japan
Stacie LOFTUS, Staff Scientist at National Human Genome Research Institute, United States of America
17:15-17:45 The genetics of oculocutaneous albinism and chemical-induced vitiligo

Tamio SUZUKI 1

1 Department Of Dermatology, Faculty Of Medicine, Yamagata University, Yamagata, Japan

17:45-18:15 Lessons learned from finding missing genetic heritability in oculocutaneous albinism

Stacie LOFTUS 1

1 Staff Scientist at National Human Genome Research Institute, Washington DC, United States of America

18:10-18:40 Modulating TGFβ signaling output in neural crest stem cells and melanoma

Lukas SOMMER 1

1 University of Zurich, Zurich, Switzerland

18:45-19:00 Cyclical Fate Restriction in the zebrafish neural crest: Ltk signalling promotes iridophore fate determination by repressing melanophore and xanthophore fates.

Karen CAMARGO SOSA 1 , Masataka NIKAIDO 2 , Noah SHRIEVER 1 , Frederico S. L. M. RODRIGUES, 1 , Saeed FARJAMI 3 , Jonathat H. P. DAWES 1 , Andrea ROCCO 3 , Makeev VSEVOLOD 4 , Robert KELSH 5

1 University of Bath, Bath, United Kingdom
2 University of Hyogo, Hyogo, Japan
3 University of Surrey, Guildford, United Kingdom
4 Vavilov Institute of General Genetics,, Moscow, Russian Federation
5 University of Bath, Batg, United Kingdom

19:00-19:15 The complexity of simple genetics: oligogenic patterns in albinism

Panagiotis SERGOUNIOTIS 1 , David GREEN 2 , Vincent MICHAD 3 , Eulalie LASSEAUX 4 , Claudio PLAISANT 4 , Tomas FITZGERALD 5 , Ewan BIRNEY 5 , Graeme BLACK 1 , Benoît ARVEILER 3

1 University of Manchester & Manchester Centre for Genomic Medicine, Manchester, United Kingdom
2 University of Manchester, Manchester, United Kingdom
3 University of Bordeaux & University Hospital of Bordeaux, Bordeaux, France
4 University Hospital of Bordeaux, Bordeaux, France
5 EMBL-EBI, Hinxton, United Kingdom

19:15-19:30 An induced suppressor mutation in mouse MITF unravels the functional role of the carboxyl-end of MITF and provides important information on the melanoma-predisposing E318K mutation in humans.

Hong Nhung VU 1 , Matthías Már VALDIMARSSON 2 , Jón H. HALLSSON 3 , Lionel LARUE 4 , Heinz ARNHEITER 5 , Neal G. COPELAND 6 , Nancy A. JENKINS 6 , Petur Orri HEIDARSSON 2 , Eiríkur STEINGRÍMSSON 1

1 Department of Biochemistry and Molecular Biology, BioMedical Center, Faculty of Medicine, University of Iceland, 102 Reykjavík, Iceland
2 Department of Biochemistry, Science Institute, School of Engineering and Natural Sciences, University of Iceland., 102 Reykjavík, Iceland
3 Department of Biochemistry and Molecular Biology, BioMedical Center, Faculty of Medicine, University of Iceland, Reykjavik, Iceland
4 Institut Curie, PSL Research University, INSERM U1021, Normal and Pathological Development of Melanocytes, Paris, France
5 Mammalian Development Section, NINDS, NIH, MD 20892-3706, United States of America
6 Mouse Cancer Genetics Program, NCI, MD 21702-1201, United States of America

Wednesday, May 31st

Hall
08:00-13:15 Reception open
Plenary 3 - Melanoma 1 Mitxelena room
Chairpersons:
Chikako NISHIGORI, Kobe University, Japan
Susana PUIG, Hospital Clínic De Barcelona, Dermatology Department, Spain
08:15-08:45 New insights in deep phenotyping and genetics of melanoma

Susana PUIG 1

1 Hospital Clínic De Barcelona, Dermatology Department, Barcelona, Spain

08:45-09:15 Plasticity in melanoma

Anja Katrin BOSSERHOFF 1

1 FAU Erlangen-Nürnberg, Erlangen, FAU Erlangen-Nürnberg, Germany

08:45-09:15 Seeds for new therapeutic strategies of malignant melanoma

Takeshi FUKUMOTO 1

1 Div. Dermatology, Dep. Internal Related, Kobe University Graduate School of Medicine, Kobe, Japan

09:45-10:00 Heterozygous bap1 knockout accelerates uveal melanoma progression

Nathalie LONGAKIT 1 , Roula FARAG 1 , Fagun JAIN 1 , Amy LUTY 1 , Catherine VAN RAAMSDONK 1

1 Life Sciences Institute, University of British Columbia, Vancouver, Canada

10:00-10:15 CTLA4 mRNA Is Downregulated by miR-155 in Regulatory T Cells, and Reduced Blood CTLA4 Levels Are Associated With Poor Prognosis in Metastatic Melanoma Patients

Mayumi FUJITA 1 , Prasanna Kumar VADDI 1 , Douglas Grant OSBORNE 1 , Andrew NICKLAWSKY 2 , Nazanin Kalani WILLIAMS 1 , Dinoop Ravindran MENON 1 , Derek SMITH 2 , Jonathan MAYER 1 , Anna REID 3 , Joanne DOMENICO 1 , Giang Huong NGUYEN 1 , William A ROBINSON 4 , Melanie ZIMAN 3 , Dexiang GAO 2 , Zili ZHAI 1

1 Department of Dermatology, University of Colorado Anschutz Medical Campus, Colorado, United States of America
2 University of Colorado Cancer Center Biostatistics Core, University of Colorado Anschutz Medical Campus, Colorado, United States of America
3 School of Medical and Health Sciences, Edith Cowan University, Western Australia, Australia
4 Department of Medicine, University of Colorado Anschutz Medical Campus, Colorado, United States of America

10:15-10:30 Targeting metabolic adaptation to breakdown resistance to targeted therapy in metastatic melanoma

Laura SOUMOY 1 , Anne-Emilie DECLÈVES 2 , Caroline ROBERT 1 , Ghanem GHANEM 3 , Fabrice JOURNE 2

1 Institut Gustave Roussy, Villejuif, France
2 University of Mons, Mons, Belgium
3 Institut Jules Bordet, Brussels, Belgium

Chillida and Axular rooms
10:30-11:00 Coffee break
Plenary 4 - Melanoma 2 Mitxelena room
Chairpersons:
Dr Robert BALLOTTI, Inserm U1065, France
Ze'ev RONAI, Sanford Burnham Prebys Medical Discovery Institute, United States of America
11:00-11:30 Coordinated control of melanoma cell proliferation, metastatic potential and immune suppression by the dsRNA helicase DDX46

Adriana SANNA 1

1 CNIO, Madrid, Spain

11:30-12:00 Melanoma Control by the TME

Ze'ev RONAI 1

1 Sanford Burnham Prebys Medical Discovery Institute, La Jolla, United States of America

12:00-12:30 Understanding the molecular mechanisms involved in uveal melanoma progression reveal new actionable vulnerabilities

Corine BERTOLOTTO 1

1 Université Côte D’Azur, Niza, France

12:30-12:45 The E-cadherin-ESR1-GRPR axis defines a sex-specific metastatic pathway in melanoma

Véronique DELMAS 1 , Jérémy RAYMOND 1 , Marie POUTEAUX 1 , Valérie PETIT 1 , Zackie AKTARY 1 , Béatrice VERGIER 2 , Lionel LARUE 1

1 Institut Curie, PSL Research University, INSERM U1021, CNRS UMR 3347, Orsay, France
2 Service de pathologie CHU de Bordeaux, Bordeaux, France

12:45-13:00 POMT1 and dystroglycan glycosylation in melanoma progression.

Israel CASTILLO GONZALEZ 1 , Gabriela RAPOZO GUIMARÃES 2 , Sophia GANDARILLAS 1 , Erasmo PERERA 1 , Mariana BORONI 2 , Prem CHAPAGAIN 1 , Lidia KOS 1

1 Florida International University, Miami, United States of America
2 Laboratório de Bioinformática e Biologia Computacional, Instituto Nacional de Cancer, Rio de Janeiro, Brazil

13:00-13:15 Small extracellular vesicle-based human melanocyte and melanoma signature

Ainhoa ALONSO PARDAVILA 1 , Andrea AGÜERA LORENTE 1 , Maria LARRINAGA 1 , Juan Manuel FALCÓN PÉREZ 2 , Mª Dolores BOYANO LÓPEZ 1 , Aintzane ASUMENDI 1 , Aintzane APRAIZ 1

1 Department of Cell Biology and Histology, Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), Bilbao, Spain
2 Exosomes Laboratory and Metabolomics Platform, Center for Cooperative Research in Biosciences (CIC bioGUNE), Bilbao, Spain

Chillida and Axular rooms
13:15-14:15 Lunch
Poster sessions Oteiza room
14:15-15:15 Poster sessions, P0-01 to PO-35

Topics: Animal models, Melanins and melanosomes, Melanoma I and II, Melanoma therapies and Pigmentation genetics. All posters will remain in exhibition during the entire meeting. See below.

Concurrent 1 - Animal models Mitxelena room
Chairpersons:
Berta SANCHEZ-LAORDEN, Institute of Neurosciences CSIC-UMH, Spain
Elizabeth PATTON, University of Edinburgh, United Kingdom
15:15-15:45 Targeting developmental lineages in melanoma

Elizabeth PATTON 1

1 University of Edinburgh, Edinburgh, United Kingdom

15:45-16:15 Microenvironmental regulation of melanoma progression

Berta SANCHEZ-LAORDEN 1

1 Institute of Neurosciences CSIC-UMH, San Juan de Alicante, Spain

16:15-16:30 Revealing the intricacies of iridosome-mediated guanine crystal formation in zebrafish iridophores: insights into acidic microenvironment, organelle maturation, and RNA signatures

Anna GORELICK ASHKENAZI 1 , Yuval BARZILAY 1 , Tsviya OLENDER 1 , Dvir GUR 1

1 Weizmann Institute of Science, Molecular Genetics Department, Rehovot, Israel

16:30-16:45 Disrupting the seed and soil crosstalk: altering the metastatic niche in melanoma to impede tumor growth

Aitor BENEDICTO GARCÍA 1 , Eva ARMENDARIZ 1 , Alba HERRERO 1 , Federico N SORIA 2 , Daniel ALONSO-ALCONADA 1 , Mª Dolores BOYANO LÓPEZ 1 , Beatriz ARTETA 1

1 Department of Cell Biology and Histology, School of Medicine and Nursing, University of the Basque Country, Leioa, Spain, Leioa, Spain
2 Achucarro Basque Center for Neuroscience, Leioa, Spain and Ikerbasque Foundation, Bilbao, Spain, Leioa, Spain

Concurrent 2 - Vitiligo Baroja room
Chairpersons:
Davinder PARSAD, Institute of Medical Education and Research (PGIMER), India
Caroline LE POOLE, Northwestern University Feinberg School of Medicine, United States of America
15:15-15:45 Vitiligo treatment: Current and emerging directed therapies

Davinder PARSAD 1

1 Institute of Medical Education and Research (PGIMER), Chandigarh, India

15:45-16:15 Dietary components align with disease activity in human vitiligo

Caroline LE POOLE 1

1 Northwestern University Feinberg School of Medicine, Chicago, United States of America

16:15-16:30 Impact of House-Dust-Mite in Vitiligo Skin: Environmental Contribution to Increased Cutaneous Immunity and Melanocyte Detachment

Hanene BZIOUECHE 1

1 Université Côte d’Azur, INSERM U1065,Centre Méditerranéen de Médecine Moléculaire, Nice, France

16:30-16:45 Dysregulated USP18-ISG15 network promotes IFN-α secretion from CD8+ T cells via LFA-1 in vitiligo

Sang Ho OH 1 , Eung Jung LEE 1 , Seung Kyung HANN 2

1 Department of Dermatology, Yonsei University College of Medicine & Cutaneous Biology Research Institute, Seoul, Republic of Korea
2 Woo and Hann's skin clinic, Seoul, Republic of Korea

Chillida and Axular rooms
16:45-17:15 Coffee break
Concurrent 3 - Advances in Melanoma Therapies: new targets, molecular mechanisms and clinical translation Mitxelena room
Chairpersons:
Alfonso BERROCAL, Medical Oncology Service, Consortium General University Hospital of Valencia and GEM, Spain
Svenja MEIERJOHANN, University of Würzburg, Institute of Pathology, Germany
17:15-17:45 Metabolic rewiring as a target in cutaneous melanoma

Imanol AROZARENA 1

1 NAVARRABIOMED-FMS-IDISNA, Pamplona, Spain

17:45-18:15 Stress adaptation in melanoma: the role of NRF2

Svenja MEIERJOHANN 1

1 University of Würzburg, Institute of Pathology, Würzburg, Germany

18:15-18:30 Identification of circRNAs involved in acquisition of BRAFi resistance in metastatic melanoma

Yanis SI AHMED 1 , Sébastien CORRE 1 , Yuna BLUM 1 , Rose-Marie FRABOULET 1 , Diane SCHAUSI 1 , Marie-Dominique GALIBERT 1

1 Institut de Génétique et Développement de Rennes, Rennes, France

18:30-18:45 Ferroptosis as a therapeutic opportunity to counteract BRAFi-resistance in melanoma

Cyrille BERRA 1 , Heloïse LECLAIR 1 , Marie-Dominique GALIBERT 1 , Sébastien CORRE 1

1 IGDR UMR6290 CNRS, Rennes, France

Concurrent 4 - Melanins Baroja room
Chairpersons:
Michal SARNA, Jagiellonian University, Poland
Kazumasa WAKAMATSU, Fujita Health University, Japan
17:15-17:35 Analysis of melanin pigmentation in human melanoma cells with different metastatic potential

Michal SARNA 1

1 Jagiellonian University, Krakow, Poland

17:35-17:55 A Chemist’s View of Melanogenesis: Update

Shosuke ITO 1

1 Fujita Health University, Toyoake, Japan

17:55-18:15 Role of vitamin D signaling in pigment cell biology

Andrzej SLOMINSKI 1

1 University of Alabama at Birmingham, Birmingham, United States of America

18:15-18:30 DHI eumelanin content revealed in human skin with varying degrees of constitutive pigmentation

Sandra DEL BINO 1 , Shosuke ITO 2 , Juliette SOK 3 , Kazumasa WAKAMATSU 2

1 L’Oreal Research and Innovation, Aulnay-sous-Bois, France, France
2 Institute for Melanin Chemistry, Toyoake, Aichi, Japan
3 L'Oreal Research & Innovation, Aulnat-sous-Bois, France

18:30-18:45 Ethanol and its metabolite, acetaldehyde, induces melanocyte activation and unique DNA damage in melanocytes

Takeshi YAMAUCHI 1 , Kimtrang T NGUYEN 1 , Zili ZHAI 1 , Akiko MATSUMOTO 2 , Bin GAO 3 , Byoung J SONG 4 , Douglas E. BRASH 5 , Mayumi FUJITA 1

1 Department of Dermatology, University of Colorado Anschutz Medical Campus, Colorado, United States of America
2 Department of Social Medicine, School of Medicine, Saga University, Saga, Japan
3 NIAAA, NIH, Maryland, United States of America
4 NIAAA, NIH, Maryland, Japan
5 Department of Therapeutic Radiology, Yale University School of Medicine, Connecticut, United States of America

Public outreach event Arriaga room
19:00- IPCC Dialogues

This is a public outreach event, in Spanish and Basque language only

Thursday, June 1st

Hall
08:00-13:15 Reception open
Plenary 5 - Biology of pigment organelles Mitxelena room
Chairpersons:
Graça RAPOSO, Institut Curie · Department of Cell Biology, France
Duarte BARRAL, NOVA Medical School, Portugal
08:15-08:45 Mechanisms of melanosome biogenesis revealed by rare genetic disease

Mickey MARKS 1

1 The Children's Hospital of Philadelphia, Philadelphia, United States of America

08:45-09:15 Shedding light on the mechanisms of melanin transfer and processing

Duarte BARRAL 1

1 NOVA Medical School, Lisboa, Portugal

09:15-09:45 Cell biology of pigmented keratinocytes: from pigment position to DNA photoprotection

Laura SALAVESSA 1

1 Institut Curie, Paris, France

09:45-10:00 Unraveling the molecular mechanisms underlying intracellular crystal formation

Rachael DEIS 1 , Tali LERER-GOLDSHTEIN 1 , Zohar EYAL 1 , Olha BAIKO 1 , Uwe HEINIG 1 , Yonghui DONG 1 , Rita MATEUS 2 , Sylvia KAUFMANN 2 , Dvir GUR 1

1 Weizmann Institute of Science, Molecular Genetics Department, Rehovot, Israel
2 Max Planck Institute of Molecular Cell Biology and Genetics, Dresden, Germany

10:00-10:15 3D ultrastructure analysis reveals the presence of abnormal macromelanosomes in keratinocytes of actinic lentigines

Charlene GAYRARD 1 , Ilse HURBAIN 2 , Virginie PIFFAUT 1 , Francoise BERNERD 1 , Graça RAPOSO 2 , Christine DUVAL 1

1 L'Oréal Research and Innovation, Aulnay-sous-Bois, France
2 Institut Curie, PSL Research University, CNRS, UMR, Paris, France

10:15-10:30 Differential uptake of exosomes by stressed and healthy melanocytes and its effect on melanogenesis.

Hitaishi KAUSHIK 1 , Davinder PARSAD 1

1 Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India

Chillida and Axular rooms
10:30-11:00 Coffee break
Plenary 6 - Melanocyte development Mitxelena room
Chairpersons:
Lionel LARUE, Institut Curie, France
Takahiro KUNISADA, Department of Tissue and Organ Development, Japan
11:00-11:15 2023 IFPCS Seiji Memorial Lecture
Distinct Functional Heterogeneity of Melanocyte Stem Cells

Thomas HORNYAK 1

1 University of Maryland, School of Medicine, Baltimore, United States of America

11:15-11:40 α-catenin during the establishment of the melanocyte lineage

Lionel LARUE 1

1 Institut Curie, Orsay, France

11:40-12:05 MITF represses neural genes to specify melanocytes

Akinori KAWAKAMI 1

1 Kyoto University Graduate School of Medicine, Kyoto, Japan

12:05-12:30 Analysis of Integrin-Dependent Cell-ECM adhesion in Melanoblast Migration During Development

Guy TANENTZAPF 1

1 University of British Columbia, Vancouver, Canada

12:30-12:45 Sex differences in melanocyte stem cell behavior reveals therapeutic strategies for re-pigmentation

Andrew WHITE 1 , Luye AN 1 , Dahihm KIM 1 , Leanne DONAHUE 1

1 Cornell University, Ithaca, NY, United States of America

12:45-13:00 The developmental origin of aortic valve melanocytes

Perony DA SILVA NOGUEIRA 1 , Daniel CHAPARRO 1 , Sana NASIM 2 , Joshua HUTCHESON 1 , Lidia KOS 1

1 Florida International University, Miami, United States of America
2 Harvard Medical School, Boston, United States of America

13:00-13:15 Uncovering Core Cell Lineages that Generate Melanoma Tumors

Hui XIAO 1 , Jessica SHIU 1 , Chi-Fen CHEN 1 , Peijie ZHOU 1 , Qing NIE 1 , Arthur D. LANDER 1 , Anand K. GANESAN 1

1 University of California, Irvine, Irvine, United States of America

Chillida and Axular rooms
13:15-14:15 Lunch
Poster sessions Chillida room
14:15-15:15 Poster sessions, PO-37 to PO-53

Topics: Melanocyte development, Molecular mechanisms of other pigmentary disorders, Signal transduction and Melanocyte environment. All posters will remain in exhibition during the entire meeting. See below.

Concurrent 5 - Signal transduction Mitxelena room
Chairpersons:
Celia JIMÉNEZ-CERVANTES, University of Murcia, Spain
Jonathan ZIPPIN, Englander Institute for Precision Medicine, United States of America
15:15-15:45 Regulation of melanosomal pH and pigmentation by distinct cAMP micro domains

Jonathan ZIPPIN 1

1 Englander Institute for Precision Medicine, New York, United States of America

15:45-16:15 Regulation of the Hair Follicle Stem Cell Niche Fate during Skin Pigmentation

Carlos CLAVEL 1

1 A*star, Singapore, Singapore

16:15-16:30 Loss of MC1R signaling implicates TBX3 in pheomelanogenesis and melanoma predisposition

H. Matthew BERNS 1 , Dawn E. WATKINS-CHOW 1 , Sizhu LU 2 , Pakavarin LOUPHRASITTHIPHOL 2 , Tongwu ZHANG 3 , Kevin M. BROWN 3 , Pedro MOURA-ALVES 4 , Colin R. GODING 2 , William J. PAVAN 1

1 National Human Genome Research Institute, National Institutes of Health, Bethesda, United States of America
2 Ludwig Institute for Cancer Research, University of Oxford, Headington, United Kingdom
3 National Cancer Institute, National Institutes of Health, Bethesda, United States of America
4 i3S-Instituto de Investigação e Inovação em Saúde, Universidade do Porto, Porto, Portugal

16:30-16:45 Unique Tetrapeptide α-MSH Analogs Rescue Human Melanocytes from Solar UV-Induced Oxidative Stress

Parth UPADHYAY 1 , Viki SWOPE 1 , Renny STARNER 1 , Zalfa ABDEL - MALEK 1

1 University of Cincinnati, Cincinnati, United States of America

Concurrent 6 - Albinism Baroja room
Chairpersons:
Lluis MONTOLIU, National Center For Biotechnology (CNB-CSIC) and CIBER of Rare Diseases (CIBERER - ISCIII), Spain
Sophie JAVERZAT, INSERM U1211 MRGM, France
15:15-15:40 Albinism: where do we stand?

Benoît ARVEILER 1

1 Université de Bordeaux, Bordeaux, France

15:40-16:05 Albinism: what have we learnt from animal models?

Lluis MONTOLIU 1

1 National Center For Biotechnology (CNB-CSIC) and CIBER of Rare Diseases (CIBERER - ISCIII), Madrid, Spain

16:05-16:30 L-Dopa, the usual suspect in OCA retinal anomalies

Sophie JAVERZAT 1

1 INSERM U1211 MRGM, BORDEAUX, France

16:30-16:45 Ultrastructure study of melanosomes from retinal pigment epithelium of OCA1A and OCA2 forms of Albinism

Aman GEORGE 1 , Mones ABU-ASAB 2 , Brian BROOKS 2

1 National Institutes of Health, Bethesda, United States of America
2 National Eye Institute, Bethesda, United States of America

Chillida and Axular rooms
16:45-17:15 Coffee break
Concurrent 7 - Molecular mechanisms of other pigmentary disorders Mitxelena room
Chairpersons:
Leah VARDY, A*STAR, Singapore
Heather ETCHEVERS, INSERM, Aix-Marseille Université, France
17:15-17:45 Polyamines: Novel Regulators Of Human Epidermal Pigmentation

Leah VARDY 1

1 A*STAR, Singapore, Singapore

17:45-18:15 Cellular diversity in large/giant congenital melanocytic nevi

Heather ETCHEVERS 1

1 INSERM, Aix-Marseille Université, Marseille, France

18:15-18:30 Possible mechanism of tranexamic acid in the treatment of refractory melasma and Riehl’s melanosis: regulating the expression of CCN1 by inhibiting plasmin

Zhongyi XU 1 , Chengfeng ZHANG 1 , Leihong Flora XIANG 1

1 Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, People's Republic of China

18:30-18:45 Melanoma in patients with xeroderma pigmentosum (XP): lessons from Japanese nationwide survey for XP and clinical practice on melanoma in XP patients

Chikako NISHIGORI 1

1 Kobe University, Kobe, Japan

Concurrent 8 - Melanocyte environment Baroja room
Chairpersons:
Dr. José Carlos GARCÍA-BORRÓN, University of Murcia, Spain
Emi K. NISHIMURA, The Institute Of Medical Science, The University Of Tokyo, Japan
17:15-17:40 Functions of Extracellular Vesicles in pigmentation and intercellular communication in the skin

Graça RAPOSO 1

1 Institut Curie · Department of Cell Biology, Paris, France

17:40-18:05 Environmental regulation of melanocyte stem cell dynamics, fate and melanomagenesis

Emi K. NISHIMURA 1

1 The Institute Of Medical Science, The University Of Tokyo, Tokyo, Japan

18:05-18:20 Analysis of apoptosis susceptibility in distinct human cutaneous melanocyte subpopulations and in melanoma cells of different subtypes and melanin status

Cristina CASALOU 1 , Jay M MAYATRA 1 , Stephanie BOLLARD 2 , Kazumasa WAKAMATSU 3 , SHOSUKE ITO 3 , Desmond J TOBIN 1

1 Charles Institute of Dermatology, University College Dublin, Dublin, Ireland
2 Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Dublin, Ireland
3 Institute for Melanin Chemistry, Fujita Health University, Aichi, Japan

18:20-18:35 Melanosomes as new cancer immune modulators of melanoma

Carmit LEVY 1

1 Tel Aviv University - School of Medicine, Tel Aviv, Israel

18:35-18:50 Lysosome specialization during keratinocyte differentiation: enlightening future views of skin homeostasis

Sarmistha MAHANTY 1 , Ptissam BERGAM 2 , Deepak NAIR 1 , Graça RAPOSO 2 , Subba RAO GANGI SETTY 1

1 Indian Institute of Science, Bengaluru, India
2 Institut Curie, PSL Research University, CNRS, UMR, Paris, France

Friday, June 2nd

Hall
08:00-13:15 Reception open
Plenary 7 - UVR and the skin Mitxelena room
Chairpersons:
Boon Kee GOH, Skin Physician At Mount Elizabeth Medical Centre, Singapore
Marie Dominique GALIBERT, Université De Rennes, France
08:15-08:45 Understanding How UV-exposure Shapes Melanoma Biology

Marie Dominique GALIBERT 1

1 Université De Rennes, Rennes, France

08:45-09:15 Impact of UVB photon density on photocarcinogenesis of the skin

Cheng Che E LAN 1

1 Kaohsiung Medical University, Kaohsiung, Taiwan, Republic of China

09:15-09:35 Benefit of an enlarged photoprotection in the UVA1 wavelengths range for preventing skin photodamage and hyperpigmentation.

Claire MARIONNET 1 , Romain DE DORMAEL 1 , Xavier MARAT 1 , Angelina ROUDOT 2 , Christelle GOLEBIEWSKI 1 , Philippe BASTIEN 1 , Caroline Tricaud TRICAUD 2 , Didier CANDAU 3 , Francoise BERNERD 1

1 L'Oréal Research and Innovation, Aulnay-sous-Bois, France
2 L'Oréal Research and Innovation, Chevilly Larue, France
3 Didier Candau Conseil, Versailles, France

09:35-09:55 The duality of melanin: opposing roles of cell-intrinsic pigment in melanoma formation

Valentina POSADA 1 , Tirzah WEISS 1 , Emma CRAWFORD 1 , Hafeez RAHMAN 2 , Tong LIU 2 , Brandon MURPHY 1 , Rebecca HENNESSEY 1 , Lianbo YU 1 , John D'ORAZIO 3 , Craig BURD 1 , Jonathan ZIPPIN 4 , Douglas GROSSMAN 2 , Christin BURD 1

1 The Ohio State University, Columbus, United States of America
2 The University of Utah Huntsman Cancer Institute, Salt Lake City, United States of America
3 University of Kentucky College of Medicine, Lexington, United States of America
4 Weill Medical College of Cornell University, New York, United States of America

09:55-10:15 The role of melanocytes´ senescence in the process of UV-induced skin aging

Ines MARTIC 1 , Pidder JANSEN-DÜRR 1 , Maria CAVINATO 1

1 University of Innsbruck – Department for Biomedical Aging Research, Innsbruck, Austria

Chillida and Axular rooms
10:15-11:00 Coffee break
Plenary 8 - Pigmentary disorders Mitxelena room
Chairpersons:
Flora XIANG, Huashan Hospital, Fudan University, People's Republic of China
Mauro PICARDO, Unicamillus International University, Italy
11:00-11:30 Photobiomodulation therapy for prevention or treatment of PIH and melasma: mechanism and clinical practice

Flora XIANG 1

1 Huashan Hospital, Fudan University, Shangai, People's Republic of China

11:30-12:00 Oxidative stress in Vitiligo: a critical review

Mauro PICARDO 1

1 Unicamillus International University, Roma, Italy

12:00-12:15 Role of CLEC12B in skin immunity

Lauriane BLOT 1

1 Centre Méditerranéen de Médecine Moléculaire (C3M), INSERM U1065, Nice, France

12:15-12:30 Unraveling Griscelli’s syndrome hypopigmentation using an in vitro model

João CHARNECA 1 , Michael HALL 1 , Uwe HANSEN 2 , Matilde NETO 1 , Duarte BARRAL 1 , Miguel SEABRA 1

1 iNOVA4Health, CEDOC, NOVA Medical School, NMS, Universidade NOVA de Lisboa, Lisbon, Portugal
2 Department of Physiological Chemistry and Pathobiochemistry, University Hospital of Münster, Münster, Germany

12:30-12:45 Defining the inhibitory effects of secreted frizzled related protein 1 on melanocytes

Daiki YAMAKOSHI 1 , Toru ATSUGI 1 , Mario MEDVEDVIC 2 , Alan B. FLEISCHER 3 , Diya MUTASIM 3 , Viki SWOPE 3 , Renny STARNER 3 , Yuki MIZUTANI 1 , Zalfa ABDEL - MALEK 4

1 KOSÉ Corporation Research Laboratories, Tokyo, Japan
2 Department of Environmental and Public Health, University of Cincinnati, Cincinnati, Ohio, United States of America
3 Department of Dermatology, University of Cincinnati, Cincinnati, Ohio, United States of America
4 Department of Dermatology, University of Cincinnati, Cincinnati, OH, United States of America

12:45-13:00 Melanin retention in keratinocytes could contribute to inflammatory environment observed in actinic lentigines

Charlene GAYRARD 1 , Elodie CONDOM 1 , Karima LABIAD-HADJI 1 , Emilie BOURREAU 1 , Emilie WARRICK 1 , Christine DUVAL 1 , Francoise BERNERD 1

1 L'Oréal Research and Innovation, Aulnay-sous-Bois, France

Chillida and Axular rooms
13:15-14:15 Lunch
Etxepare room
14:15-15:15 General assembly PASPCR
Elhuyar room
14:15-15:15 General assembly JSPCR
Baroja room
14:15-15:15 General assembly ESPCR
Poster sessions Axular room
14:15-15:15 Poster sessions, PO-54 to PO-67

Topics: Innovative technologies, Pigmentary disorders, UVR and the skin and Clinical Treatment of pigmentary diserders. All posters will remain in exhibition during the entire meeting. See below.

Arriaga room
14:15-15:15 General assembly ASPCR
Concurrent 9 - Innovative technologies Mitxelena room
Chairpersons:
Dr. Santos ALONSO, Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Spain
Muriel CARIO-ANDRÉ, Bordeaux University, France
15:15-15:45 Geniouskin: the first pigmented artificial skin for clinical use

Muriel CARIO-ANDRÉ 1

1 Bordeaux University, Bordeaux, France

15:45-16:15 Spatial Lipidomics of melanoma

Jose Andres FERNANDEZ 1

1 University of the Basque Country (UPV/EHU), Leioa, Spain

16:15-16:30 Discovery of 2-mercaptonicotinoyl glycine, a new potent lightening agent exhibiting a unique mode of action investigated in vitro and in vivo

Peggy SEXTIUS 1 , Romain DE DORMAEL 1 , Janney QIU 2 , Guillaume LEREAUX 1 , Emilie WARRICK 1 , Xavier MARAT 1 , Stéphane DIRIDOULLOU 1

1 L’Oréal Research and Innovation, Aulnay, France, Aulnay sous bois, France
2 L’Oréal Research and Innovation, Pudong, China, Aulnay sous bois, People's Republic of China

16:30-16:45 Magnetic nanodisks in melanocytes and melanoma cell cultures for cancer treatment

Raquel ZURBANO 1 , Carolina REDONDO 1 , Izaro SOLOZABAL 1 , Mª Dolores BOYANO LÓPEZ 2 , Rafael MORALES 1

1 Department of Physical Chemistry, University of the Basque Country UPV/EHU, Leioa, Spain
2 Department of Cell Biology and Histology, School of Medicine and Nursing, University of the Basque Country, Leioa, Spain, Leioa, Spain

Concurrent 10 - Clinical treatment of pigmentary disorders Baroja room
Chairpersons:
Rosa IZU, Dermatology department of the Basurto University Hospital, Spain
Chengfeng ZHANG, Huashan Hospital, Fudan University, People's Republic of China
15:15-15:30 The therapeutic effects of dermal rejuvernation in melasma using non-Invasive radiofrequency device

Kyoungchan PARK 1 , Soon-Hyo KWON 2 , Jung-im NA 3 , Chang-hun HUH 3

1 Department of Dermatology, Eulji Medical Center at Uijeongbu, Eulji University, Uijeongbu, Gyeonggido, Republic of Korea
2 Department of Dermatology, Kyung Hee University Hospital at Gangdong, Kyung Hee University School of Medicine, Seoul, Republic of Korea
3 Department of Dermatology, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea

15:30-15:50 585-590 nm Light-emitting diodes (LEDs): A rising star for melasma treatment

Chengfeng ZHANG 1

1 Huashan Hospital, Fudan University, Shanghai, People's Republic of China

15:50-16:10 The Challenges in Treating Melasma

Boon Kee GOH 1

1 Skin Physician At Mount Elizabeth Medical Centre, Singapore, Singapore

16:10-16:25 Targeting the Elevated IFN-α in Vitiligo Patients by Human Anti- IFN-α Monoclonal Antibody Hampers Direct Cytototoxicity in Melanocyte

Chau Yee NG 1 , Cheng Lung KU 2

1 Department of Dermatology, Chang Gung Memorial Hospital, Taoyuan City 333, Taiwan, Province of China
2 Department of Immunology, Chang Gung University, Taoyuan City, Taiwan, Province of China

Chillida and Axular rooms
16:45-17:15 Coffee break
Council meeting 2 Arriaga room
16:45-17:15 Council meeting 2 IFPCS
General assembly Mitxelena room
17:15-17:45 IFPCS
Closure Mitxelena room
Chairperson: Dr. José Carlos GARCÍA-BORRÓN, University of Murcia, Spain
17:45-18:15 Closure
Journey through the Spectacular Landscapes of Melanocortin 1 Receptor

Zalfa ABDEL - MALEK 1

1 University Of Cincinnati College Of Medicine, Cincinnati, United States of America

18:15-18:30 IPCC 2023 Farewell.

Handing over the torch to Davinder Parsad on behalf of ASPCR, organizers of the next IPCC2026 in New Delhi, India.

Poster sessions

Wednesday, May 31st

Poster sessions Oteiza room
PO-01 Crosstalk with keratinocytes causes GNAQ oncogene specificity in melanoma

Catherine D. VAN RAAMSDONK 1 , Oscar URTATIZ , Amanda HAAGE , Guy TANENTZAPF 1

1 University of British Columbia, Vancouver, Canada

PO-02 Role of Schwann cells in melanoma progression

Francisco GRACIÁ QUILES 1 , Javier RODRÍGUEZ-BAENA , Angel MÁRQUEZ , Marta ARUMÍ-PLANAS , M. Angela NIETO , Jose P. LÓPEZ-ATALAYA , Berta SANCHEZ-LAORDEN 1

1 Institute of Neurosciences CSIC-UMH, San Juan de Alicante, Spain

PO-03 An oligodendrocyte progenitor cell-like population emerges in melanoma brain metastasis

Pablo BALLESTEROS-MARTÍNEZ 1 , Javier RODRÍGUEZ-BAENA , Angel MÁRQUEZ , Marta ARUMÍ-PLANAS , Francisco GRACIA-QUILES , Jose P. LOPEZ-ATALAYA , Berta SANCHEZ-LAORDEN 1

1 Institute of Neurosciences CSIC-UMH, San Juan de Alicante, Spain

PO-04 MGRN1 AS A PHENOTYPIC DETERMINANT OF HUMAN MELANOMA CELLS AND A POTENTIAL BIOMARKER

Marta ABRISQUETA , Sonia CERDIDO , Jose SÁNCHEZ-BELTRÁN 1 , Idoya MARTÍNEZ-VICENTE , Javier SOLER DIAZ , Cecilia HERRAIZ 1 , Ana LAMBERTOS , Conchi OLIVARES 2 , Arrate SEVILLA 3 , Santos ALONSO 4 , María Dolores BOYANO , José Carlos GARCÍA-BORRÓN 1 , Celia JIMÉNEZ-CERVANTES 1

1 University of Murcia, Murcia, Spain
2 Universidad de Murcia / Instituto Murciano de Investigación Biosanitaria, El Palmar (Murcia), Spain
3 University of the Basque Country (UPV/EHU), Leioa, Spain
4 Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Leioa, Spain

PO-05 Androgen receptor in melanoma

Feng LIU-SMITH 1 , Nupur SINGH , Jude KHATIB , Chi-Yang CHIU , Jianjian LIN , Tejesh Surender PATEL

1 University of Tennessee, Germantown, United States of America

PO-06 A new AI tool to improve melanoma diagnosis and prognosis in early-stage melanoma patients

Cristina PENAS LAGO 1 , Jesus GARDEAZABAL 2 , Ana SANCHEZ-DIEZ , Jose Luis DIAZ-RAMÓN , Estíbaliz GARROTE , Javier RASERO , Aintzane APRAIZ 1 , Sandra SEIJO , Cristina LOPEZ-SARATXAGA , Pedro Maria DE LA PEÑA , Goikoana CANCHO-GALÁN , Verónica VELASCO , Arrate SEVILLA 1 , David FERNÁNDEZ , Itziar CUENCA , Jesús CORTÉS , Santos ALONSO 3 , Aintzane ASUMENDI 4 , Mª Dolores BOYANO LÓPEZ 5 , Rosa IZU 6

1 University of the Basque Country (UPV/EHU), Leioa, Spain
2 Hospital Universitario Cruces, Barakaldo, Spain
3 Faculty of Science and Technology, University of the Basque Country (UPV/EHU), Leioa, Spain
4 Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), Leioa, Spain
5 Chair of the IPCC 2023, University of the Basque Country (UPV/EHU), Bilbao, Spain
6 Dermatology department of the Basurto University Hospital, Bilbao, Spain

PO-07 SOX21 - Transcriptional Regulation in Malignant Melanoma

Nicole RACHINGER 1 , Silke KUPHAL , Anja Katrin BOSSERHOFF 2

1 Friedrich-Alexander Universität Erlangen-Nürnberg, Erlangen, Germany
2 FAU Erlangen-Nürnberg, Erlangen, FAU Erlangen-Nürnberg, Germany

PO-08 Copy number variations and fusion genes in driver mutation-negative melanoma

Tokimasa HIDA 1 , Masashi IDOGAWA , Junji KATO , Kohei HORIMOTO , Sayuri SATO , Yukiko KINIWA , Shintaro SUGITA , Masae OKURA , Ryuhei OKUYAMA , Takashi TOKINO , Hisashi UHARA 1

1 Sapporo Medical University, Sapporo, Japan

PO-09 Tumor cell-derived sphingosine 1-phosphate promotes loss of adhesion to keratinocytes and contributes to primary melanoma invasion

Lorry CARRIÉ-MORELLA 1 , Justine NOUJARÈDE , Virginie GARCIA , Maxime GRIMONT , Anaïs EBERHARDT , Elodie MUCHER , Matthieu GENAIS , Anne SCHREUDER , Stéphane CARPENTIER , Bruno SÉGUI , Marie-Pierre ROLS , Thierry LEVADE , Susana PUIG 2 , Olivier HAROU , Stéphane DALLE , Julie CARAMEL , Laure GIBOT , Joëlle RIOND , Nathalie ANDRIEU-ABADIE

1 Cancer Research Center of Toulouse, Toulouse Cedex 3, France
2 Hospital Clínic De Barcelona, Dermatology Department, Barcelona, Spain

PO-10 Transcriptional co-activators YAP1 and TAZ are drivers of vasculogenic mimicry in melanoma.

Stephen MOORE 1 , Claire A WU , Yuangqing ZHANG , Rashi PUROHIT , Jason W LUI , Hiroshi TOKUO , Deborah LANG

1 Boston University, Boston, United States of America

PO-11 MICAL2, upregulated by α-catenin, induces invasion in melanoma

Lara ARAKTINGI 1 , Pierre SOHIER , Nour ZIDI , Jérémy RAYMOND , Zackie AKTARY , Nisa CHAROENCHON , Valérie PETIT , Lionel LARUE 1

1 Institut Curie, Orsay, France

PO-12 Enhanced intercellular adhesion by induction of E-cadherin and inhibition of Cdc42-GTPase in MGRN1-silenced human melanoma cells

Sonia CERDIDO OCHOA 1 , Marta ABRISQUETA , María CASTEJÓN , Jose SÁNCHEZ-BELTRÁN 1 , Ana LAMBERTOS , Conchi OLIVARES 2 , José Carlos GARCÍA-BORRÓN 1 , Celia JIMÉNEZ-CERVANTES 1 , Cecilia HERRAIZ 1

1 University of Murcia, Murcia, Spain
2 Universidad de Murcia / Instituto Murciano de Investigación Biosanitaria, El Palmar (Murcia), Spain

PO-13 Investigating the role of primary cilia and the ciliome in melanoma phenotype switching

Louise BRENNAN 1 , Emma WILKINSON , Sarah ALLINSON , Richard MORT 1

1 Lancaster University, Lancaster, United Kingdom

PO-14 Lysosomal function and intracellular position determine the malignant phenotype in melanoma

Ida ERIKSSON 1 , Petra WÄSTER , Linda VAINIKKA 1 , Karin ÖLLINGER

1 Department of Biomedical and Clinical Sciences (BKV), Linköping, Sweden

PO-15 Targeting novel biomarkers in melanoma by proteomic and network biology analysis of the surfaceome

Tibor HAJDÚ 1 , Emese ZSIGRAI , Patrik KOVÁCS , Minh Ngoc NGUYEN , Róza ZÁKÁNY , András BALAJTHY , David J BOOCOCK , Peter N PUSHPARAJ , Csaba MATTA

1 University of Debrecen, Department of Anatomy, Histology and Embryology, Debrecen, Hungary

PO-16 The impact of UV radiation on proliferation, migration, and invasion in malignant melanoma

Öllinger KARIN 1 , Linda VAINIKKA 2 , Linda RÖßLER

1 Linköping University, Linköping, Sweden
2 Department of Biomedical and Clinical Sciences (BKV), Linköping, Sweden

PO-17 Unraveling the molecular mechanism underlying uric acid crystal formation in medaka leucophore cells

Yuval BARZILAY 1 , Rachel DEIS , Zohar EYAL , Anna GORELICK ASHKENAZI 2 , Ziv PORAT , Iddo PINKAS , Neta VERSANO , Smadar ZAIDMAN , Dvir GUR 1

1 Weizmann Institute of Science, Rehovot, Israel
2 Weizmann Institute of Science, Molecular Genetics Department, Rehovot, Israel

PO-18 Depletion of tumor-reactive astrocytes diminishes melanoma growth in the brain

Eva ARMENDARIZ 1 , Alba HERRERO 1 , Federico N. SORIA , Jon Ander ALART , Daniel ALONSO-ALCONADA , Mª Dolores BOYANO LÓPEZ 2 , Beatriz ARTETA 1 , Aitor BENEDICTO

1 University of the Basque Country (UPV/EHU), Leioa, Spain
2 Chair of the IPCC 2023, University of the Basque Country (UPV/EHU), Bilbao, Spain

PO-19 Hepatic stellate cells favor melanoma metastasis through tumor microenvironment modulation

Alba HERRERO 1 , Aitor BENEDICTO , Eva ARMENDARIZ 1 , Mª Dolores BOYANO LÓPEZ 2 , Beatriz ARTETA 1

1 University of the Basque Country (UPV/EHU), Leioa, Spain
2 Chair of the IPCC 2023, University of the Basque Country (UPV/EHU), Bilbao, Spain

PO-20 A Spontaneous Melanoma Mouse Model Applicable For A Longitudinal Chemotherapy And Immunotherapy Study

Kevinn EDDY 1 , Mohamad Naser Eddin EDDIN , Allison L. Isola ISOLA , Christina Marinaro MARINARO , Maryam Abdur Rasheed RASHEED , Joseph Campagnolo CAMPAGNOLO , Sanjana Putta PUTTA , John Sauer Jr. SAUER , Anna Chaly CHALY , Katie B. Freeman FREEMAN , Jeffrey C. Pelletier PELLETIER , Anna Fateeva FATEEVA , Philip Furmanski FURMANSKI , Allen B. Reitz REITZ , Suzie Chen CHEN

1 Rutgers University, Piscataway, United States of America

PO-21 Revealing the intricacies of iridosome-mediated guanine crystal formation in zebrafish iridophores: insights into acidic microenvironment, organelle maturation, and RNA signatures

Anna GORELICK ASHKENAZI 1 , Yuval BARZILAY 2 , Tsviya DVIR GUR , Dvir GUR 2

1 Weizmann Institute of Science, Molecular Genetics Department, Rehovot, Israel
2 Weizmann Institute of Science, Rehovot, Israel

PO-22 Identification and Validation of Autophagy-Related Genes in Vitiligo

Yiwen YANG 1 , Xiuyi WU , Xiaoli LU , Chen WANG , Leihong XIANG , Chengfeng ZHANG 2

1 Department Of Dermatology, Huashan Hospital, Fudan University, Shanghai, People's Republic of China
2 Huashan Hospital, Fudan University, Shanghai, People's Republic of China

PO-23 Biomarkers for early detection of repigmentation in non-segmental vitiligo patients after standard of care treatment.

Rosalie LUITEN 1 , Vidhya NARAYAN , Wouter OUWERKERK , Saskia CHIELIE , Nathalie VAN UDEN , Martin-Alexander SCHNEIDER , R.B. KJELLERUP , C LOESCHE , M HANSER , Elizabeth MCNAMARA , Marcel BEKKENK , Albert WOLKERSTORFER

1 Amsterdam Univerisity Medical Center, Amsterdam, Netherlands

PO-24 Effects of marginal melanocyte infection by varicella-zoster virus (VZV) on the spread of segmental vitiligo lesions: An ultrastructural and anatomo-clinical study

Laila BENZEKRI 1 , Muriel CARIO-ANDRÉ 2 , Jérôme LAMBERT , YVON GAUTHIER

1 Mohammed V University, Rabat, Morocco
2 Bordeaux University, Bordeaux, France

PO-26 Twenty years of Vitiligo: the experience of an Italian tertiary centre

Maria Efenesia BAFFA 1 , Roberto MAGLIE , Stefano SENATORE , Carlo PIPITÒ , Silvia MORETTI , Emiliano ANTIGA

1 University of Florence, firenze, Italy

PO-27 Role of CXCR3 and its primary ligands in inducing melanocyte apoptosis in segmental and non-segmental vitiligo pathogenesis.

Laveena KAUSHAL 1 , Niharika SRIVASTAVA , Dr. Vinod KUMAR , Dr. Davinder PARSAD

1 Post Graduate Institute of Medical Education and Research, Chandigarh, India

PO-28 Clinical Importance of Autoantibodies to Sox 10 and Lamin A/C as Prognostic Factors in Sera from Vitiligo Patients

Ki Ho KIM 1 , Dongwha YOO 1

1 Dong-A University Hospital, Busan, Republic of Korea

PO-29 The risk of non-melanoma skin cancer in vitiligo patients: a systematic review and meta-analysis on the association, and the potential mechanisms involved.

Alex ROOKER 1 , Wouter OUWERKERK , Marcel W. BEKKENK , Rosalie M. LUITEN , Walbert J. BAKKER

1 Amsterdam University Medical Center, Amsterdam, Netherlands

PO-30 The expression and function of JAK3 and TEC family kinases in the pathogenesis of vitiligo.

Emma HOLTAPPELS 1 , Marcel BEKKENK , Rosalie LUITEN 1 , Walbert BAKKER 1 , Elisabeth JASPARS

1 Amsterdam Univerisity Medical Center, Amsterdam, Netherlands

PO-31 Improvement of vitiligo metabolic state

Federica PAPACCIO 1 , Barbara BELLEI 1 , Monica OTTAVIANI , Andrea D'ARINO , Silvia CAPUTO , Mauro TRUGLIO , Lorenzo SCIUTO , Alessia PACIFICO , Paolo IACOVELLI , Mauro PICARDO 2

1 San Gallicano Dermatological Institute, IRCCS, Roma, Italy
2 Unicamillus International University, Roma, Italy

PO-32 Analyzing resistance of AXL- and/or MITF-expressing melanoma cells to immunotherapy

Walbert BAKKER 1 , Marcella WILLEMSEN , J. BULGARELLI , S.K. CHAUHAN , D. ANGELI , R.R. LEREIM , I. DAVIDSON , J.A. KYTE , M. i GUIDOBON , R. M. LUITEN

1 Amsterdam Univerisity Medical Center, Amsterdam, Netherlands

PO-33 ATP1A1 is a new promising target for melanoma treatment that can be inhibited by its physiological ligand bufalin to restore targeted therapy efficacy

Fabrice JOURNE 1 , Ahmad NAJEM 2 , Ghanem GHANEM , Laura SOUMOY 3

1 Institut Jules Bordet, Brussels, Belgium
2 Institut Jules Bordet-Ulb, Bruxelles, Belgium
3 Institut Gustave Roussy, VIllejuif, France

PO-34 Inhibition of melanoma tumor growth by PHBs targeting

Serena SABBAH 1 2 , Ahmad NAJEM 3 , Ghanem E. GHANEM , Fabrice JOURNE , Laurent DÉSAUBRY

1 Free University of Brussels, Brussels, Belgium
2 Jules Bordet Institute, Brussels, Belgium
3 Institut Jules Bordet-Ulb, Bruxelles, Belgium

PO-35 A negative charge and a carboxyl terminus are necessary for the phosphatidylserine-induced phagocytosis of extracellular melanosome clusters by dermal fibroblasts

Hideya ANDO 1 , Satoshi YOSHIMOTO , Moemi YOSHIDA , Masayuki YAGI , Masamitsu ICHIHASHI

1 Okayama University of Science, Okayama, Japan

Thursday, June 1st

Poster sessions Chillida room
PO-37 Melanin pigments internalization by keratinocytes

Laura SALAVESSA 1 , Silvia BENITO-MARTINEZ , Graça RAPOSO 2 , Cédric DELEVOYE 1

1 Institut Curie, Paris, France
2 Institut Curie · Department of Cell Biology, Paris, France

PO-38 Rabβa regulates melanin exocytosis and transfer induced by keratinocyte-conditioned medium

Luís Filipe CARRIÇO CABAÇO 1

1 NOVA Medical School, Universidade NOVA de Lisboa, Lisbon, Portugal

PO-39 A multicistronic allele of Pmel yielding highly specific CreERT2 mediated recombination in melanoblasts and melanocytes

Louise BRENNAN 1 , Emma WILKINSON , Olivia HARRISON , Zoe CRANE-SMITH , Philippe GAUTIER , Margaret KEIGHREN , Peter BUDD , Karthic SWAMINATHAN , Laura MACHESKY , Sarah ALLINSON , Ian JACKSON , Richard MORT 1

1 Lancaster University, Lancaster, United Kingdom

PO-40 Exploring the Formation of Highly Reflective Guanine Crystals in Iridophore Cells

Tali LEMCOFF 1 , Avital WAGNER 2 , Benjamin A. PALMER

1 Ben Gurion University of the Negev, Beer Sheva, Israel
2 Ben-Gurion University Of The Negev, Beersheva, Israel

PO-41 MAHOGUNIN RING FINGER 1 IS INVOLVED IN THE REPLICATIVE STRESS RESPONSE IN MELANOCYTIC CELLS

Jose SÁNCHEZ-BELTRÁN 1 , Marta ABRISQUETA , Idoya MARTÍNEZ-VICENTE , Conchi OLIVARES 2 , Cecilia HERRAIZ 1 , Celia JIMÉNEZ-CERVANTES 1 , José Carlos GARCÍA-BORRÓN 1

1 University of Murcia, Murcia, Spain
2 Universidad de Murcia / Instituto Murciano de Investigación Biosanitaria, El Palmar (Murcia), Spain

PO-42 A VIS-À-VIS COMPARISON OF WILDTYPE AND VARIANT MELANOCORTIN 1 RECEPTOR SIGNALING WITH EMPHASIS ON PROTECTION AGAINST OXIDATIVE DAMAGE TO DNA

Marta ABRISQUETA , Sonia CERDIDO , Lidia PADILLA , Conchi OLIVARES 1 , Ana LAMBERTOS , José Carlos GARCÍA-BORRÓN 2 , Cecilia HERRAIZ 2 , Celia JIMÉNEZ-CERVANTES

1 Universidad de Murcia / Instituto Murciano de Investigación Biosanitaria, El Palmar (Murcia), Spain
2 University of Murcia, Murcia, Spain

PO-43 The role of MC1R in melanogenesis signaling: cAMP and beyond

Samuel GRONDIN 1 , Zuhal ERASLAN , Maftuna YUSAPOVA , Jaewon YOU , Ramiro IGLESIAS-BARTOLOME , Jonathan ZIPPIN 2

1 Weill Cornell Medicine, New York, United States of America
2 Englander Institute for Precision Medicine, New York, United States of America

PO-44 Unsuspected consequences of synonymous and missense variants in OCA2 can be detected in blood samples.

Elina MERCIER 1 , Vincent MICHAUD , Angèle SEQUEIRA , Eulalie LASSEAUX , Claudio PLAISANT , Smail HADJ-RABIA , Sandra WHALEN , Dominique BONNEAU , Anne DIEUX-COESLIER , Fanny MORICE-PICARD , Benoît ARVEILER 2 , Sophie JAVERZAT 3

1 MRGM - U1211, Bordeaux, France
2 Université de Bordeaux, Bordeaux, France
3 INSERM U1211 MRGM, BORDEAUX, France

PO-45 Generating by CRISPR tools and phenotyping new mouse models of albinism with patient-specific mutations.

Ana María GUARDIA CARRIÓN 1 , Almudena FERNÁNDEZ , Andrea MONTERO , Marta CANTERO , Julia FERNÁNDEZ , Virginie CHOTARD , Oksana KUTSYR , Henar ALBERTOS-ARRANZ , Carla SÁNCHEZ-CASTILLO , Xavier SÁNCHEZ-SÁEZ , Alexandra REBSAM , Nicolás CUENCA , Lluis MONTOLIU 2

1 Centro Nacional de Biotecnología, Madrid, Spain
2 National Center For Biotechnology (CNB-CSIC) and CIBER of Rare Diseases (CIBERER - ISCIII), Madrid, Spain

PO-46 Melanin synthesis in the test tube: seeking of the simple tool to understand the mechanism of oculocutaneous albinism.

Monika DOLINSKA 1 , Isabella OSUNA , Yuri SERGEEV

1 National Institutes of Health, Bethesda, United States of America

PO-47 Prediction of postinflammatory hyperpigmentation after laser treatment from dermoscopic findings of solar lentigo

Hwa Jung RYU 1 , Jong Hee LEE , Jeong Eun KIM 2 , Jeong Hyun SHIN , Sang Ho OH 3 , Si Hyung LEE , You Chan KIM

1 Ansan Hospital, Korea University, Ansan, Republic of Korea
2 Hanyang University College of Medicine, Seoul, Republic of Korea
3 Yonsei University College Of Medicine, Seoul, Republic of Korea

PO-48 Design of a new molecule proven to be safe and effective for topical depigmenting and antiaging methods

Alfredo MARTÍNEZ-GUTIÉRREZ 1 , Eloy PENA-RODRÍGUEZ , Susana GÓMEZ-ESCALANTE , Sergio PASCUAL , Luis G LUIS S , Mari Carmen GONZÁLEZ

1 Mesoestetic Pharma Group, Viladecans, Spain

PO-49 Integrated analysis using epidermis from solar lentigo lesions by whole genome bisulfite sequencing and RNA sequencing

Takako SHIBATA 1 , Tomoya UCHIYAMA 2 , Daigo INOUE , Koji OBA , Taiki TSUTSUI , Makoto KUNISADA , Chikako NISHIGORI 3

1 MIRAI Technology Institute, Shiseido Co., Ltd., Yokohama,
2 Shiseido Company, Limited, Yokohama, Japan
3 Kobe University, Kobe, Japan

PO-50 EFFECT OF THE CULTURE CONDITIONS OF EPIDERMAL MELANOCYTES ON THEIR MORPHOLOGY AND FUNCTIONALITY

Maddalen RODRIGUEZ ASTIGARRAGA 1 , Cristina ROMO VALERA 1 , Ainara AGINAGA ETXAMENDI , Jon ARLUZEA 2 , Mª Dolores BOYANO LÓPEZ 3 , Miguel PÉREZ-GARRASTACHU 2 , Noelia ANDOLLO 1

1 University of the Basque Country (UPV/EHU), Leioa, Spain
2 University of the Basque Country (UPV/EHU), Bilbao, Spain
3 Chair of the IPCC 2023, University of the Basque Country (UPV/EHU), Bilbao, Spain

PO-51 CEMIP regulates skin fibroblast activation: implications in the melanoma microenvironment

Maria LARRINAGA 1 , Andrea AGÜERA-LORENTE , Ainhoa ALONSO-PARDAVILA , Iera HERNÁNDEZ-UNZUETA , Mª Dolores BOYANO LÓPEZ 2 , Juan Manuel FALCÓN-PEREZ , Aintzane ASUMENDI 3 , Aintzane APRAIZ 4

1 University of the Basque Country (UPV/EHU), Sopela, Spain
2 Chair of the IPCC 2023, University of the Basque Country (UPV/EHU), Bilbao, Spain
3 Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), Leioa, Spain
4 University of the Basque Country (UPV/EHU), Leioa, Spain

PO-52 Tyrosine mediates the phenotypic plasticity of melanoma by modulating oxidative stress both in vitro and in an animal model

Ahmad NAJEM 1 , Jasper WOUTERS , Mohammad KRAYEM , Florian RAMBOW , Malak SABBAH , François SALES , Ahmad AWADA , Stein AERTS , Fabrice JOURNE 2 , Jean-Christophe MARINE , Ghanem Elias GHANEM

1 Institut Jules Bordet-Ulb, Bruxelles, Belgium
2 Institut Jules Bordet, Brussels, Belgium

PO-53 Melanocytes in the corneoscleral limbus: much more than suppliers of melanin for limbal epithelial stem cells.

Noelia ANDOLLO 1 , Cristina ROMO-VALERA , Maddalen RODRIGUEZ-ASTIGARRAGA , Jon ARLUZEA 2 , Miguel PÉREZ-GARRASTACHU

1 University of the Basque Country (UPV/EHU), Leioa, Spain
2 University of the Basque Country (UPV/EHU), Bilbao, Spain

Friday, June 2nd

Poster sessions Axular room
PO-54 Contribution of the Visible Light color domains in sun-induced pigmentation

Claire MARIONNET 1 , Virginie PIFFAUT , Pascale RENOUX , Jun SASAI , Hussein JOUNI , Maria ORTIZ , Etienne HUGUET , Emilie PLANEL , Luc DUTEIL , Francoise BERNERD

1 L'Oreal Research and Innovation, Aulnay-sous-Bois, France

PO-55 Risk-taking personality influences sun exposure habits: the role of CADM2

Carolina BONILLA 1

1 Universidade de São Paulo, São Paulo, Brazil

PO-56 Chronic inflammation is evidenced in actinic lentigine from European and Asian volunteers

Christine DUVAL 1 , Emilie BOURREAU , Emilie WARRICK , Karima LABIAD-HADJI , Constance ALVAREZ-DUCHESNE , Francoise BERNERD

1 L'Oreal Research & Innovation, Aulnay sous Bois, France

PO-57 Is Periorbital Melanoses a window for Metabolic Syndrome? A case series

Dr. Shubhali SALUNKHE 1 , DR. VIJAY ZAWAR ZAWAR

1 DR. VASANTRAO PAWAR MEDICAL COLLEGE, HOSPITAL AND RESEARCH CENTRE, NASHIK, INDIA, NASHIK, India

PO-58 Altered gut microbiome diversity aligns with disease activity in vitiligo

Zhussipbek MUKHATAYEV 1 , Yerkhanat KHUANBAI , Nurlybek KATKENOV , Almagul KUSHUGULOVA

1 National Laboratory Astana, Nazarbayev University, Astana, Kazakhstan

PO-59 Relating disease severity to treatment efficacy by HSP70iQ435A for vitiligo

Zhussipbek MUKHATAYEV 1 , Rohan SHIVDE , Emilia DELLACECCA , Dinesh JAISHANKAR , Caroline LE POOLE 2

1 National Laboratory Astana, Nazarbayev University, Astana, Kazakhstan
2 Northwestern University Feinberg School of Medicine, Chicago, United States of America

PO-60 The comparison of 590nm light-emitting diodes and 1064nm Q-switched Nd:YAG laser as treatment for melasma

Shanglin JIN 1 , Xiaoxi DAI , Yijie XUAN , Chengfeng ZHANG 2 , Flora XIANG 3

1 Fudan University Huashan Hospital, Shanghai, People's Republic of China
2 Huashan Hospital, Fudan University, Shanghai, People's Republic of China
3 Huashan Hospital, Fudan University, Shangai, People's Republic of China

PO-61 Lipid imaging mass spectrometry for the identificacion of lentigo maligna and primary melanoma

Cristina HUERGO 1 , Javier MARTÍN , Ignacio ZABALZA , Juan L. ARTOLA , Rosa M. MARTÍ , Aintzane ASUMENDI 2 , Olatz FRESNEDO , Begoña OCHOA , Mª Dolores BOYANO LÓPEZ 3 , José A. FERNÁNDEZ

1 University of the Basque Country (UPV/EHU), Leioa, Spain
2 Faculty of Medicine and Nursing, University of the Basque Country (UPV/EHU), Leioa, Spain
3 Chair of the IPCC 2023, University of the Basque Country (UPV/EHU), Bilbao, Spain

PO-62 Uncovering the molecular mechanisms of crystal Formation in iridophores through cryo-EM and proteomics

Dvir GUR 1 , Zohar EYAL , Rachael LIN DEIS , Tali LERRER-GOLDSHTEIN , Anna GORELICK ASHKENAZI 2 , Lothar HOUBEN , Neta VARSANO

1 Weizmann Institute of Science, Rehovot, Israel
2 Weizmann Institute of Science, Molecular Genetics Department, Rehovot, Israel

PO-63 Feasibility of High Resolution, Real-time Optical Coherence Tomography in the Evaluation of Vitiligo: A Prospective Longitudinal Follow-up Study

Chau Yee NG 1 , Yi-Jing LAI

1 Chang Gung Memorial Hospital, Taipei, Taiwan, Republic of China

PO-64 Novel synergistic combination of active ingredients for melasma topical therapy

Alfredo MARTÍNEZ-GUTIÉRREZ 1 , Eloy PENA-RODRÍGUEZ , Susana GÓMEZ-ESCALANTE , Mari Carmen GONZÁLEZ , Luis S LUIS G

1 Mesoestetic Pharma Group, Viladecans, Spain

PO-65 Effectiveness of compound glycyrrhizin in combination with phototherapy in child vitiligo patients

Li ZHANG 1 , Leihong XIANG

1 Huashan Hospital, Fudan University, Shanghai, People's Republic of China

PO-66 Cysteamine/isobionic-amide complex : A novel skin depigmenting combination for the treatment of skin hyperpigmentary disorders

Behrooz KASRAEE 1 , Laure DIRLEWANGER 2

1 Scientis SA, Geneve,
2 Scientis, Geneva, Switzerland

PO-67 Targeting keratinocytes in vitiligo skin: an alternative strategy?

Emanuela BASTONINI 1 , Daniela KOVACS 1 , Stefania BRIGANTI , Monica OTTAVIANI , Alessia PACIFICO , Paolo IACOVELLI , Mauro PICARDO 2

1 San Gallicano Dermatological Institute, IRCCS, Roma, Italy
2 Unicamillus International University, Roma, Italy

Rooms

Room Level

Hall

Level 0

Mitxelena

Level 0

Chillida

Level 1

Oteiza

Level 1

Arriaga

Level 2

Baroja

Level 2

In this link you can see the different rooms.

Organisers

  • espcr
  • IFPCS
  • UPV / EHU Zientzia
  • UPV / EHU Medikuntza

Scientific Endorsement

  • GEM
  • bioCruces Bizkaia

Public Sponsors

  • Eusko Jaurlaritza, Osasun saila

Collaborators

  • Bristol Meyers
  • Euskampus
  • Innoprot
  • MSD
  • Proquinorte
  • Teknovas